This is interesting as well as surprising. Gordon Shepherd, a neurologist at the Yale School of Medicine has a book out titled, Neuroenology: How the Brain Creates the Taste of Wine.
Quite a bit of this article deals with the premise that wine molecules have no taste, but it is the brain which creates the sensation which we perceive as taste. Ok, I'm not smart enough to go into all that since it seems that the taste buds in our mouths must have something to do with flavor and taste. But here's the real interesting part:
"Enjoying a glass of wine makes the grey matter in our brains work harder than it would any other human activity — like listening to music or solving a math problem. Shepherd states that smelling and drinking wine engages our entire brain and requires “exquisite control of one of the biggest muscles in the body."
In effect, nosing the wine and drinking it is great for our brains.
But it warns that tiny sips of wine are key to a good brain workout, not big gulps. haha. I have never seen anyone drink wine with big gulps, beer yes, wine no. Also said, spitting your sip out prevents you from appreciating the flavor.
Who spits their sip of wine out? Maybe a wine taster/tester, but most of us aren't sipping and spitting our wine.